Cite This Article. The Burkholderia cepacia complex is an important group of pathogens in patients with cystic fibrosis CF. Although evidence for patient-to-patient spread is clear, microbial factors facilitating transmission are poorly understood. To identify microbial clones with enhanced transmissibility, we evaluated B. A total of isolates from the B.
Treatments to cure long-term infections with Burkholderia cepacia in people with cystic fibrosis
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Scott A. Persons with cystic fibrosis CF are susceptible to chronic pulmonary infection due to certain Burkholderia species, but it is not clear whether this typically involves persistent infection with the same strain or sequential infection with distinct strains. We analyzed Burkholderia isolates recovered from serial sputum cultures from patients with CF receiving care in CF treatment centers in the United States. Genotyping was performed by random amplified polymorphic DNA typing or pulsed-field gel electrophoresis.
Jump to navigation. We reviewed the evidence for antibiotic treatment to cure early infection with Burkholderia cepacia complex in people with cystic fibrosis and prevent it becoming permanent. Cystic fibrosis is an inherited disease and people who have this disease produce large amounts of thick mucus which is difficult to clear. This mucus blocks up their lungs and digestive systems.
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